Maryville Treatment Center is a prison facility for male inmates that require minimum security, and is located on the former motherhouse of the Sisters of St Francis of Maryville, a Christian congregation in Maryville, Missouri. It can house 561 offenders, about half of which are provided treatment for a minimum of six months. The remaining half are typically pre-release inmates.
The motherhouse was built during the late 1940s and was popularly known for its distinctive yellow steeple on the bluff above the One Hundred and Two River. It converted into prison treatment center in December of 1996 and, for the most part, was not welcomed by local residents.